Should GPs prescribe vitamin B compound strong tablets to alcoholics? PMC

Lipopolysaccharide is recognized by the Toll-like receptor (TLR) 4 complex, which is expressed on immune cells as well as parenchymal cells, and induces activation of inflammatory cytokines. Chronic alcohol exposure sensitizes Kupffer cells to lipopolysaccharide-induced inflammatory cytokine best vitamins for recovering alcoholics production [5,11]. Additionally, alcohol can cause hepatotoxicity directly or indirectly through its metabolites by various other mechanisms. Edible plants such as fruits, vegetables, spices, grains, and teas have been reported to be effective against ALD via these various mechanisms [12].

b vitamins for alcoholics

The Nutrition Risk Screening 2002 and Malnutrition Universal Screening Tool are recommended tools to assess nutritional status. They are valid tools for screening hospitalized patients for the risk of malnutrition and are recommended by the European Society for Clinical Nutrition and Metabolism [22,23]. The Royal Free Hospital-Nutritional Prioritizing Tool is also considered excellent for predicting malnutrition risk in cirrhosis patients [24]. In this article, we review the nutritional therapies that health care providers should be aware of when treating patients with ALD.

Are There Risks Associated with Mixing Alcohol and Supplements?

Alcoholics with cirrhosis tend to have low vitamin E levels in the liver [129], while alcoholics without cirrhosis generally have normal vitamin E levels. Oxidative stress plays a central role in alcohol-induced pathogenesis. Vitamin E supplementation restores the normal oxidative reduction status, reduces apoptosis, and prevents oxidative stress [130]. Vitamin E administration ameliorates learning and memory deficits induced by perinatal ethanol exposure and increases hippocampal brain-derived neurotrophic factor levels in a dose-dependent manner [131]. However, its usefulness in alcoholic liver disease remains unclear.

  • Too much alcohol can cause inflammation in your stomach lining and pancreas.
  • BetterHelp offers affordable mental health care via phone, video, or live-chat.
  • Alcohol interacts with neurotransmitters including gamma-aminobutyric acid.
  • After implementing the protocol, Shiling analyzed three months of data and found that of 57 patients admitted to CeDAR for alcohol use disorder, 22 received IV thiamine.
  • Microbial therapy such as probiotics improve ALD by restoring normal intestinal flora and strengthening the intestinal barrier [10].

However, recommendations vary depending on the pathophysiology of ALD and the presence or absence of glucose intolerance [54]. Among carbohydrates, excessive intake of fructose, which is commonly used commercially in soft drinks and other products, should be avoided [55]. Fructose in food and drink has been significantly correlated with the degree of inflammation and fibrosis, and is also a risk factor for the development of liver cancer [56]. Vitamin C helps to keep the skin healthy, and plays an equally important role in the health of bones, teeth and blood vessels. Deficiencies in vitamin C can cause symptoms that include irritability, weakness and muscle fatigue. The best source of vitamin C in the United States is orange juice from frozen concentrate (more of the vitamin is preserved when the oranges are frozen).

Treating thiamine deficiency

Vitamins are essential for aiding the liver after alcohol misuse by helping with detoxification, regeneration, and metabolism. Research published in 2022 found that individuals who were alcohol dependent had significantly lower levels of both zinc and magnesium compared to the control group. Alcohol use disorder (AUD) can lead to severe deficiency in several vitamins and minerals. In addition, mixing these substances can cause liver strain and gastrointestinal distress. Consult your doctor about drinking and any medications or supplements you are currently taking. This article covers the importance of vitamin supplementation for drinkers and how it affects their bodies.

  • Among the most popular vitamins touted on the labels of such drinks is vitamin B12 – a nutrient known to help with energy, but usually not in the way the industry advertises.
  • When you drink, the process of metabolizing alcohol utilizes nutrients in your body.
  • Anxiety is a symptom of alcohol withdrawal, so increasing your zinc intake may help ease withdrawal.
  • Research suggests certain B vitamins can help treat alcoholic liver disease by alleviating alcohol-induced oxidative stress8.

However, resting energy expenditure (REE) is usually elevated in AUD patients, even though they often do not eat and only drink alcohol. Malnutrition due to impaired digestion and nutrient absorption from alcohol and organ damage are common complications in patients with conventional ALD. These patients are predominantly characterized by decreased body weight, muscle or fat mass, muscle strength, visceral protein levels, and immune function [15]. Thus, patients with ALD often develop protein–energy malnutrition (PEM). The occurrence of malnourishment in ALD patients is a multifactorial event that includes altered olfactory and taste perception, appetite-related hormonal changes, and altered gut flora [2]. Patients admitted with severe AH often have a history of heavy alcohol consumption.

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When the level of essential nutrients decreases in your liver the bloodstream is called upon to replenish it. As a result, body cells are deprived of critical nutrients and normal body functions can suffer. While taking vitamins can help manage symptoms caused by chronic alcohol use, they are most effective alongside detoxification and rehabilitation. Keep in mind that taking supplements while continuing to consume alcohol can overwork your liver and lead to other medical complications. Heavy drinkers are prone to nutrient deficiencies that can cause fatigue and weakness, skin and hair issues, metabolism problems, bone fractures, bruising, bleeding, and depression. Fortunately, taking vitamins regularly and achieving good nutrition can help alleviate some of these adverse effects.

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